Common use

Modafresh promotes wakefulness and is used to treat excessive daytime sleepiness caused by narcolepsy, obstructive sleep apnea (OSA), or shift work sleep (SWS) disorder. Modafresh does not treat the underlying disorder, it only makes people feel more awake. Modafresh does not take the place of other treatments for narcolepsy or OSA. These should be continued while you are taking Modafresh.

Dosage and direction

Take Modafresh exactly as prescribed by your doctor. Do not take this medicine in larger or smaller amounts or for longer than recommended. Modafresh is usually taken 1 time each day. Usual adult dose for Narcolepsy: Modafresh 200 mg orally daily in the morning. Take Modafresh in the morning (when you wake up) if you suffer from daytime sleepiness due to narcolepsy or OSA. Take Modafresh 1 hour before the start of a work shift if you are taking it to treat work-time sleep disorders. You may take the tablet with or without food.

Precautions

To make sure Modafresh is safe for you, tell your doctor about all your medical conditions, including if you have: angina (chest pain); cirrhosis or other liver problem; kidney disease; high blood pressure, heart disease, or history of heart attack; a history of mental illness or psychosis; history of alcoholism or drug addiction; are pregnant or intending to become pregnant; are breastfeeding or intending to breastfeed.

Contraindications

Do not take Modafresh if you have ever had an allergic reaction or skin rash while taking modafinil, Provigil, or armodafinil (Nuvigil).
Modafresh is not approved for use by anyone younger than 17 years old.
Modafresh may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Avoid other dangerous activities until you know how Modafresh will affect your level of wakefulness.
Avoid drinking alcohol while taking Modafresh.

Possible side effect

The most common side effects of Modafresh are: a headache; dizziness; feeling nervous or anxious; back pain; nausea; diarrhea; an upset stomach; sleep problems (insomnia); poor appetite; a stuffy nose.
Weight loss is not a recognized side effect of Modafresh, although nausea and poor appetite are common side effects of Modafresh that may lead to weight loss.

Drug interaction

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take: Medications that are substrates for CYP3A4/5 (such as contraceptives, cyclosporine, midazolam, and triazolam). These may not be as effective when taken in combination with modafinil; Medications that are substrates for CYP2C19 (such as phenytoin, diazepam, propranolol, omeprazole, and clomipramine) may have their effect prolonged by modafinil, leading to an increased risk of side effects or toxicity; Warfarin; Monoamine oxidase (MAO) inhibitors, such as isocarboxazid, phenelzine, selegiline, and tranylcypromine.

Missed dose

Do not take a dose of Modafresh if you remember your dose but it is almost bedtime or you do not plan to be awake for several hours. Skip the missed dose. Do not take extra medicine to make up for the missed dose the next day.

Overdose

Seek emergency medical attention.

Storage

Store Modafresh tablets at room temperature away from moisture and heat. Keep away from children and pets.